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引用本文:王灵杰1,高晓忠2.嵊州刺果毛茛的化学成分研究[J].中国现代应用药学,2009,(6):460-462.
WANG Lingjie1, GAO Xiaozhong2.Studies on the Chemical Constituents in Ranunculus muricatus L.[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,(6):460-462.
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嵊州刺果毛茛的化学成分研究
王灵杰1,高晓忠2
作者单位
王灵杰1,高晓忠2  
摘要:
目的对嵊州刺果毛茛的化学成分进行分离和结构鉴定。方法采用溶剂提取和各种色谱法分离得到8个化合物,运用多种波谱技术鉴定其化学结构。结果8个化合物分别鉴定为豆甾-4-烯-3,6-二酮(I)、豆甾醇(II)、白头翁素(Ⅲ)、七叶内酯二甲醚(IV)、β-谷甾醇(V)、原儿茶醛(VI)、原儿茶酸(Ⅶ)和木犀草素(Ⅷ)。结论化合物 I,Ⅳ,V,Ⅵ为首次从刺果毛茛中分离得到。
关键词:  刺果毛茛  豆甾-4-烯-3,6-二酮  豆甾醇  白头翁素  七叶内酯二甲醚  β-谷甾醇  原儿茶醛  原儿茶酸  木犀草素
DOI:
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基金项目:
Studies on the Chemical Constituents in Ranunculus muricatus L.
WANG Lingjie1, GAO Xiaozhong2
Abstract:
OBJECTIVE To isolate and determine the chemical constituents from Shengzhou Ranunculus muricatu L. . METHODS Eight compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS, 1H-NMR,13C-NMR and DEPT. RESULTS The structures were elucidated as stigmasta-4-ene-3,6-dione(I),stigmasterol(Ⅱ),anemonin (Ⅲ),scoparone (IV),β-sitostero1(V), protocatechuic aldehyde (Ⅵ),protocatechuic acid(Ⅶ) and 1uteolin (Ⅷ), respectively. CONCLUSION Compounds( I,Ⅳ,V,Ⅵ) were isolated from Ranunculus muricatus for the first time.
Key words:  Ranunculus muricatus L.  stigmasta-4-ene-3,6-dione  stigmasterol  anemonin  scoparone  β-sitostero1  protocatechuic aldehyde  protocatechuic acid  luteolin
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