二阶导数光谱法测定盐酸氟西汀胶囊的溶出度

狄平平; 宓一英; 鲍忠芸; 洪铭; 闻俊;张培棣

引用本文:	狄平平,宓一英,鲍忠芸,洪铭,闻俊;张培棣.二阶导数光谱法测定盐酸氟西汀胶囊的溶出度[J].中国现代应用药学,1995,(5):36-38.
	Di Ping-ping, Bao Zhong-yun et al.Dissolution of Fluoxetine Hydrochloride Capslues by Second OrderDerivative UV Spectrophotometry[J].Chin J Mod Appl Pharm(中国现代应用药学),1995,(5):36-38.

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二阶导数光谱法测定盐酸氟西汀胶囊的溶出度
狄平平,宓一英,鲍忠芸,洪铭,闻俊;张培棣

作者	单位
狄平平,宓一英,鲍忠芸,洪铭,闻俊;张培棣

摘要:

介绍周二阶导数光谱法测定盐酸氟西汀胶囊溶出度,可以消除采用紫外光谱法直接测定溶出度时因辅料和胶壳吸收对结果带来的影响。本方法准确快速,口收率在99.67～100.7%之间,适用于药品的质量控制。

关键词: 盐酸氟西汀胶囊溶出度二阶导数光谱法

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Dissolution of Fluoxetine Hydrochloride Capslues by Second OrderDerivative UV Spectrophotometry

Di Ping-ping, Bao Zhong-yun et al

Abstract:

A second order detivative UV spectrophotometry was used todelermine the dissolution of FIuoxetine Hydrochloride Capsules. The absorption effect of adjuvant to dissolutionwas eliminated bythis method which is precise,rapid,and proper to the control of dru

Key words: fluoxetine hydrochloride capsule, dissolution, second order derivative spectrophotometry