| 引用本文: | 董善士,杨敬荣,祝昱,王丽华.盐酸环丙沙星软膏的含量测定和稳定性研究[J].中国现代应用药学,1994,(3):26-27. |
| Dong Shanshi; Yang Jingrong; Zhu Yu; Wang Lihua.HPLC Determination of Ciprofloxacin Hydrochloride Ointment and Studies on its Stability[J].Chin J Mod Appl Pharm(中国现代应用药学),1994,(3):26-27. |
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| 摘要: |
| 用反相液相色谱法成功地对盐酸环丙沙星软膏的含量进行了测定,平均回收率为98.94%,RSD为0.56%.同时对本品稳定性进行了考察,试验结果证明,本品对光和热都不稳定,故必须遮光、密封、在阴凉处保存. |
| 关键词: 盐酸环丙沙星软膏 反相液相色谱法 稳定性 |
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| HPLC Determination of Ciprofloxacin Hydrochloride Ointment and Studies on its Stability |
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Dong Shanshi; Yang Jingrong; Zhu Yu; Wang Lihua
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| Abstract: |
| Ciprofloxacin hydrochloride in its ointment formulation was determined by a HPLCmethod. The HPLC system consisted of an ODS column (150 46 mm, id, 5 m) with citrate(0.4 mol/L)-methanol-acetonitrile (10:4:1) elution and UV detection at 254 um. The stabilit |
| Key words: Ciprofloxacin hydrochloride Ointment Stability |
