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引用本文:邹方友,周莉,熊宜军.复方夏天无片治疗轻度癌痛的临床观察[J].中国现代应用药学,2011,28(3):268-270.
ZOU Fangyou,ZHOU Li,ZHOU Li.Clinical Observation on Treatment of Mild Cancer Pain with Compound Rhizoma Corydalis Decumbentis[J].Chin J Mod Appl Pharm(中国现代应用药学),2011,28(3):268-270.
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复方夏天无片治疗轻度癌痛的临床观察
邹方友, 周莉, 熊宜军
江西省抚州市第一人民医院临床药学室,江西 抚州 344000
摘要:
目的 观察复方夏天无片治疗轻度癌痛的疗效。方法 将76例符合入组标准的轻度癌痛病患者随机分成两组各38例。治疗组用复方夏天无片口服,每日3次,每次2片,连续使用2周。对照组用非甾体抗炎药双氯酚酸钠肠溶片,每日3次,每次50 mg,方法及疗程均与治疗组相同。结果 治疗组总有效率89.5%,对照组的总有效率88.2%,两组比较无显著性差异(P>0.05);治疗组不良反应发生率仅为7.89%,且症状比较轻微;而对照组双氯酚酸钠不良反应发生率为23.68%,尤其是胃肠反应及肝、肾功能损害比较突出,症状也比较明显,患者耐受性较差,经统计分析有极显著差异(P<0.01)。结论 复方夏天无片治疗轻度癌痛与双氯酚酸钠肠溶片效果相似,但不良反应发生率少。
关键词:  轻度癌痛  复方夏天无片  镇痛效果  不良反应
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Clinical Observation on Treatment of Mild Cancer Pain with Compound Rhizoma Corydalis Decumbentis
ZOU Fangyou, ZHOU Li, ZHOU Li
The Clinic Pharmacy Department of the First People's Hospital of Fuzhou City, Fuzhou 344000, China
Abstract:
OBJECTIVE To observe the effect of compound Rhizoma Corydalis Decumbentis treating mild cancer pain. METHODS Seventy-six patients with the standard of mild pain were divided into two groups randomly. Thirty-eight cases in treatment group were given 2 tablets compound Rhizoma Corydalis Decumbentis each time, three times a day, lasting 2 weeks. Control group was given diclofenac sodium, 50 mg each time, three times a day. The methods and treating periods of treatment group and control group were same. RESULTS The total effective rate in treatment group was 89.5%, and control group was 88.2%, two groups have no significant difference (P>0.05). The side effect of treatment group was only 7.89%, and with minor symptoms, the control group was 23.68%, especially the gastrointestinal reaction and liver damage and kidney damage were very prominent, the symptoms were obvious, and patient tolerance was poor. By statistical analysis, there was significant difference(P<0.01). CONCLUSION The effect of treating mild cancer pain with compound Rhizoma Corydalis Decumbentis is the same with diclofenac sodium, while the side effect is less than the latter.
Key words:  mild cancer pain  compound Rhizoma Corydalis Decumbentis tablet  analgesic effect  side effect
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