哌拉西林/他唑巴坦给药方案研究进展

Research Progress for Dosage Regimen of Piperacillin Sodium and Tazobactam Sodium

摘要: 目的介绍哌拉西林/他唑巴坦给药方案的研究进展。方法通过查阅近年来国内外相关文献，选取核心期刊进行综述。结果哌拉西林/他唑巴坦的给药方案包括24 h持续静脉滴注、延长输注时间静脉滴注、间断静脉滴注。结论 24 h持续静脉滴注能更有效地发挥哌拉西林/他唑巴坦的抗菌作用、降低细菌耐药性发生，并减少医疗费用。

Abstract: OBJECTIVE To introduce the research progress for dosage regimen of piperacillin/tazobactam. METHODS The domestic and international articles were reviewed to summarize the core periodicals. RESULTS The dosage regimen of piperacillin/tazobactam included continuous infusion, extended-infusion and intermittent infusion. CONCLUSION Continuous infusion of piperacillin/tazobactam in 24 h is more effective to treat the bacterial infectious disease, which can reduce the resistance to bacterium and reduce treatment costs.