电感耦合等离子体质谱法测定五层共挤输液用袋硅含量及迁移量

Determination of Si and Si Migration into Infusion of 5-Layer Co-extrusion Bags by ICP-MS

摘要: 目的建立五层共挤输液用袋材料中硅含量及输液中硅迁移量的电感耦合等离子体质谱测定法(ICP-MS)。方法采用微波消解对样品进行消解处理，在确定的光谱条件下用ICP-MS测定法测定硅的含量。结果硅在1.5~5.0 μg·mL^-1内呈良好的线性关系(r=0.999 5)；硅含量测定的平均回收率为98.4%(RSD=2.3%)。结论该方法准确、灵敏、简便，适用于对五层共挤输液用袋材料中硅含量及输液中硅迁移量的测定。

Abstract: OBJECTIVE To develop a method for determination of Si and Si migration into infusion of 5-layer co-extrusion bags by ICP-MS. METHODS The sample was digested by microwave digestion, the content of Si was determined by ICP-MS under certain working conditions. RESULTS Si had a linear range between 1.5-5.0 μg·mL^-1(r=0.999 5). The average recovery of Si was 98.4%(RSD=2.3%). CONCLUSION This method is accurate, sensitive and simple, it can be used for determination of Si and Si migration into infusion of 5-layer co-extrusion bags.