5-Fu/PLGA 微球的制备
Preparation of Poly(DL-lactide-co-glycolide)Microspheres Containing 5-Fluorouracile
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摘要: 以可生物降解高分子材料乳酸—羟乙酸共聚物(PLGA)为载体,以5—氟脲嘧啶(5-Fu)为活性药物,用相分离—凝聚法制备了可供肿瘤动脉栓塞化疗用微球,并进行了初步的微球体外药物释放试验。Abstract: An attempt is being made to develop poly(DL-lactide-co-glycolide)(PLGA)microspheres containing 5-fluorouracile(5-Fu)as a new anticancer preparation for tumourarterial chemoembolization therapy.Thus,PLGA was synthesized by ring-opening polymerization of DL
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